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hoang_van_tamyhn
18-09-2009, 06:25
mình chỉ biết nó gặp trong bệnh VKDT có teo tuyến lệ tuyến nước bọt thôi.Giúp mình một số bệnh nữa với.Cảm ơn nhìu

bluerose
19-09-2009, 00:01
Chào bạn,

Hội chứng Sjogren được xác định bởi viêm kết giác mạc khô, khô miệng và viêm khớp dạng thấp được nhà khoa học Henrik Sjogren (Thụy Điển) phát hiện năm 1933.

Đây là bệnh lý miễn dịch viêm lan tỏa các tuyến ngoại tiết và toàn bộ bề mặt của mắt.

Hội chứng Sjogren có thể xảy ra nguyên phát hay thứ phát sau một bệnh tự miễn khác như bệnh Lupus hay bệnh đái tháo đường type I.

Sjögren's syndrome is also associated with rheumatic disorders such as rheumatoid arthritis, and it is rheumatoid factor positive in 90 percent of cases.

The hallmark symptoms of the disorder are dry mouth and dry eyes (part of what are known as sicca symptoms). In addition, Sjögren's syndrome may cause skin, nose, and vaginal dryness, and may affect other organs of the body, including the kidneys, blood vessels, lungs, liver, pancreas, and brain.

hoang_van_tamyhn
19-09-2009, 09:48
cảm ơn bạn nha

Future-Dr
20-09-2009, 14:36
Hội chứng Sjogren thì Em đã biết nhưng Điều trị nó thì thế nào Chị bluerose bật mí cho Em với.

bluerose
20-09-2009, 23:41
Chào Future-Dr,

Chủ yếu điều trị triệu chứng và thuốc ức chế miễn dịch:

The treatment of patients with Sjogren's syndrome is directed toward the particular areas of the body that are involved and complications, such as infection. There is no cure for Sjogren's syndrome.

Dryness of the eyes can be helped by artificial tears, eye-lubricant ointments at night, and minimizing the use of hair dryers. When dryness becomes more significant, the ophthalmologist can plug the tear duct closed so that tears cover the eye longer. Cyclosporine eyedrops (Restasis) are recently approved medicated drops that can reduce the inflammation of the tear glands improving their function. Signs of eye infection (conjunctivitis), such as pus or excessive redness or pain, should be evaluated by the doctor.

The dry mouth can be helped by drinking plenty of fluids, humidifying air, and good dental care to avoid dental decay. The glands can be stimulated to produce saliva by sucking on sugarless lemon drops or glycerin swabs. Additional treatment for the symptom of dry mouth are prescription medications that are saliva stimulants, such as pilocarpine (Salagen) and cevimeline (Evoxac). These medications should be avoided by people with certain heart diseases, asthma, or glaucoma. Artificial saliva preparations can ease many of the problems associated with dry mouth. Many of these types of agents are available as over-the-counter products, including toothpaste, gum, and mouthwash (Biotene). Vitamin E oil has been used with some success. Infections of the mouth and teeth should be addressed as early as possible in order to avoid more severe complications. Diligent dental care is very important.

Saltwater (saline) nasal sprays can help dryness in the passages of the nose. Vaginal lubricant should be considered for sexual intercourse.

Hydroxychloroquine (Plaquenil) has been helpful for some manifestations of Sjogren's syndrome. Serious complications, such as vasculitis, can require immune-suppression medications, including cortisone (prednisone and others) and/or azathioprine (Imuran) or cyclophosphamide (Cytoxan).

Infections, which can complicate Sjogren's syndrome, are addressed with appropriate antibiotics. Cancer of the lymph glands (lymphoma), a rare complication of Sjogren's syndrome, is treated independently.